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Education:
- B.A., Columbia College, 1959
M.D., New York University School of Medicine, 1963
- 1963-1964
Medical Internship
Downstate University Medical Center
- 1964-1965
Medical Junior Assistant Residency
Downstate University Medical Center
- 1965-1967
Research Fellowship, National Heart Institute
Peter Bent Brigham Hospital, Harvard Medical School
- 1967-1968
Senior Resident in Medicine
Massachusetts General Hospital Harvard Medical School
Military Service:
- 1968-1970
Major, U.S. Air Force (MC). Staff Cardiologist Wilford Hall USAF Medical Center
Staff Positions:
- 1968-1970
Staff Cardiologist
Wilford Hall USAF Hospital, Lackland AFB, Texas
- 1970-1977
Director, Cardiac Catheterization Laboratory
Yale University School of Medicine
- 1970-1973
Assistant Professor of Medicine
Yale University School of Medicine
- 1973-1977
Associate Professor of Medicine
Yale University School of Medicine
- 1978-Associate Clinical Professor of Medicine
Yale University School of Medicine
Professional Honors or Recognition:
- Fellow , American Federation for Clinical Research
- Fellow, American College of Cardiology
- Fellow, American Heart Association Council on Clinical Cardiology
- Fellow, American College of Physicians
- Fellow, Ezra Stiles College, Yale University
- Member, Advisory Panel on Cardiovascular Drugs,
U S Pharmacopeia
- Member, American College of Physician Executives
Board Certification:
- Diplomate, American Board of Internal Medicine 1970
- Subspecialty Board in Cardiovascular Diseases 1971
Hospital Positions:
- Former Member , Pharmacy and Therapeutics Committee , Hospital of St. Raphael.
- Former Member of Utilization Review Committee, Hospital of St. Raphael.
- Chairman of Cardiac Rehabilitation Committee, Hospital of St. Raphael 1981-1982.
- President of Medical Staff, Chairman of Medical Board, Yale-New Haven Hospital, 1982-1983.
- Chairman, Credentials Committee, Yale-New Haven Hospital, 1983-1984.
- At Large Member, Medical Board, Yale-New Haven Hospital, 1984-1986.
- Community Representative, Cardiology Section, Yale-New Haven Hospital, 1986-1988.
- Board Member, Hospital of St. Raphael IPA, 1989-1994.
- Member, Executive Committee, Department of Medicine, Yale-New Haven Hospital 1989-1991.
- Member, Internship Selection Committee, Department of Medicine, Yale-New Haven Hospital 1989- .
- Member, Advisory Committee,Care Coordinator Program, Yale-New Haven Hospital, 1995-present.
- Member of Pharmacy and Therapeutics Committee, Yale-New Haven Hospital, 2001- .
- Member, Credentials Committee, Hospital of St. Raphael, September, 2001- .
Community Medical Positions:
- Chairman, Health Systems Planning Committee, New Haven County Medical Association, 1986-1988.
- President, Physicians' Association of New Haven County, 1989-1993.
- Representative to Connecticut State Medical Society House of Delegates, 1986-present.
- Board of Governors, New Haven County Medical Association, 1986 - present.
- Secretary, Greater New Haven Division, Connecticut Heart Association, 1986-1988.
- Chairman, Cardiac Rehabilitation Committee, Greater New Haven Division, Connecticut HeartAssociation, 1986.
- Councilor, New Haven County, to Connecticut State Medical Society Council, 1991- 1998.
- Third District Congressional Medical Advisory Committee Chairman, 1987-1992.
Editorial Positions:
- Editorial Board, "Catheterization and Cardiovascular Diagnosis"
- Reviewer for: American Journal of Cardiology; Book Review Department of New England Journal of Medicine
- Contributor to "Op - Ed " Pages, New Haven Register and Hartford Courant
Managed Care Activities:
- Executive Committee and Board of Governors, Physicians' Association of New Haven County, 1984-1986
- President, Physicians' Association of New Haven County, (reported analyses of managed care organizations to membership of
the New Haven Counry Medical Associaltion) , 1986-1990
- President, Specialty Net, LLC (Multispecialty Network) 1995-2000
- Chairman, Steering Committee, Cardionet ( Cardiology Network) , 1995-96
- President, Board of Managers, Cardionet LLC ( Cardiology Network) 1996-1998.
- Member, Quality Utilization Management Committee , CIGNA Health Care of Connecticut , 1995-1996
- Member, Quality Management Committee, CIGNA Health Care of Connecticut, 1997 - present.
- Vice Chair, Executive Committee, Yale Cardiology Network, 1998 - .
- Medical Director, Yale Cardiology Network, 1999- .
Original Articles:
- Wolfson, S., Robbins, S.I., Krasnow, N.: Treatment of Cardiac arrhythmias with beta-adrenergic blocking
agents. Amer. Heart J. 72:177, 1966.
- Wolfson, S., et al.: Propranolol and angina pectoris. Amer. J. Cardiology. 18:345, 1966.
- Wolfson, S., and Gorlin, R.: Physiological and clinical aspects of beta-adrenergic blockage. Annals N.Y. Acad. Sciences
139:1003, 1967.
- Wolfson, S., Herman, M.V., Sullivan, J.M., Gorlin, R.: Conversion of atrial fibrillation and flutter by
Propranolol. Brit. Heart J. 29:305, 1967.
- Matloff, J.S., Wolfson, S., Gorlin, R., Harken, D.E.: Control of post-cardiac surgical tachycardias with
Propranolol. Circ. Suppl. II-133, 1967.
- Amsterdam, E., Wolfson, S., and Gorlin, R.: New aspects of the placebo response i angina. Amer. J. Cardiol. 24:305,
1969.
- Wolfson, S., and Gorlin, R.: Cardiovascular pharmacology of Propranolol in man. Circ. 40:501, 1969.
- Rose, L.I., Lowe, S.L., Carroll, D.R., Wolfson, S., and Cooper, K.H.: Serum lactate dehydrogenase changes after muscular
exertion. J. Appl. Physio. 28:279, 1971.
- Salzman, S.H., Wolfson, S., Jackson, B., Schechter, E.: Epinephrine infusion in man: Standardization, normal
response, and abnormal response in idiopathic hypertrophic subaortic stenosis.. Circ. 43:137, 1971.
- Wolfson, S., Rose, L.I., Bousser, J.E., Parisi, A.F., Acosta, A.E., Cooper, K.H., Schechter, E.: Serum enzyme levels
during exercise in patients with coronary artery disease: Effects of training. Amer. Heart J. 84:478, 1972.
- Lee, R.V., Drabinsky, M., Wolfson, S., Cohen, L.S., Atkins, E.: Pyrogen reactions from cardiac catheterization. Chest
63:757, 1973.
- Kisslo, J., Wolfson, S., Ross, A., Pasternak, R., Hammond, G.L., Cohen, L.S.: Ultrasound assessment of left ventricular
function following aortocoronary saphenous vein bypass grafting. Circ. 47-48, Suppl III-156, 1973.
- Fernandez, D., Rosenthal, J.E., Cohen, L.S., Hammond, G.L., Wolfson, S.: Alcohol-induced Prinzmetal variant
angina. Amer. J. Cardiol. 32:238, 1973.
- Bryson, A.L., Parisi, A.F., Schechter, E., Wolfson, S.: Life-treatening ventricular arrhythmias induced by
exercise. Cessation after coronary bypass surgery. Amer. J. Cardiol. 36:995, 1975.
- Wong, S., Langou R.A., Cohen, L.S., Wolfson, S.: Retrograde catheterization of the left atrium in idiopathic hypertrophic
subaortic stenosis. Amer. J. Cardiol. 36:62, 1975.
- Wolfson S., Grand, D., Ross, A.M., Cohen, L.S.: Risk of death related to coronary arteriography: Role of left coronary
lesions. Amer. J. Cardiol. 37:210, 1975.
- Zaret, B.L., Vlay, S.C., Freedman, G.M., Wolfson, S., Cohen, L.S.: Quantitative relationships between potassium-43
imaging and left ventricular cineangiography following myocardial infarction in man. Circ. 52:1076, 1975.
- Berger, H.J., Speroff, L., Wolfson, S.: Pentobarbital anesthesia: Lack of effect on venous prostaglandins in
dogs. Prostaglandins 2:499, 1976.
- Olson, E.G., Goodyer, A.V.N., Langou, R.A., Cohen, L.S. and Wolfson, S.: N-dimethylisopropyl propranolol: Effects on
myocardial oxygen demands. Circ. 53:501, 1976.
- Berger, H.J., Zaret, B.L., Speroff, L., Cohen, L.S., and Wolfson, S.: Regional cardiac prostaglandin release during
myocardial ischemia in anesthetized dogs. Circ. Res. 38:566, 1976.
- Wolfson, S., Costin, J.C.: Physical conditioning as therapy for angina pectoris. Conn. Medicine 40:527, 1976.
- Farry, J., Hammond, G.L., Cohen, L.S., Wolfson, S.: Development of atherosclerosis in a saphenous vein coronary bypass
graft. Ann. Int. Med. 85:479. 1976.
- Zaret, B.L., DiCola, V.C., Donabedian, R.K., Puri, S., Wolfson, S., Freedman, G.S., Cohen, L.S.: Dual radionuclide study of
myocardial infarction: Relationships between myocardial uptake of potassium-43, technetium-99m stannous pyrophosphate, regional myocardial blood flow and creatine phosphokinase
depletion. Circulation 53:422-428, 1976.
- Michaelson, S.P., Wolfson, S.: Treatment of supraventricular arrhythmia with propranolol. Cardiovascular Medicine 1:213,
1976.
- Ross, A.L., Hammond, G.L., Cohen, L.S., Wolfson, S.: Angiographic evaluation of saphenous vein bypass
grafts: Artifactual "occlusion" caused by dual sources of flow. Amer. J. Cardiol. 39:384, 1977.
- Langou, R.A., Wolfson, S., Edwin, G.O., Cohen, L.S.: Effects of orthostatic postural changes on myocardial oxygen demands.
39:418, 1977.
- Berger, H.J., Zaret, B.L., Speroff, L., Cohen, L.S., Wolfson, S.: Cardiac prostaglandin release during myocardial ischemia
induced by atrial pacing in patients with coronary artery disease. Amer. J. Cardiol. 39:487, 1977.
- Kelley, M.J., Wolfson, S., Marshall, R.: Single coronary artery from the right sinus of Valsalva: Angiography, anatomy
and clinical significance. Am. J. Roentgenol. 128:257, 1977.
- Kelley, M.J., Wolfson, S.: Lessons learned from coronary arteriography. Cardiovascular Progress March/April, 1977.
- Schrumpf, J.D., Sheps, D.S., Wolfson, S., Aronson, A.L., Cohen, L.S.: Altered hemoglobin-oxygen affinity with long-term
propranolol therapy in patients with coronary artery disease. Am. J. Cardiol. 40:76, 1977.
- Michaelson, S.P., Wolfson, S.: Role of propranolol in treatment of angina pectoris. Cardiovascular Medicine 3:331, 1978.
- Langou, R.A., Cohen, L.S., Sheps, D., Wolfson, S.: Intraventricular conduction during coronary arteriography in patients with
pre-existing conduction abnormalities. Invest. Radiol. Nov/Dec., 1977.
- Langou, R.A., Cohen, L.S., Sheps, D., Wolfson, S., Glenn, W.W.L.: Ondine's curse: Hemodynamic response to diaphragm
pacing (electrophrenic respiration). Amer. Heart J. 95:295, 1978.
- Wolfson, S., Karsh, D.S., Langou, R.A., Geha, A.S., Hammond, G.L., Cohen, L.S.: Modification of intra-aortic balloon catheter
to permit introduction by cardiac catheterization techniques. Amer. J. Cardiol. 41:733, 1978.
- Alexander, J., Holder, A.R., Wolfson, S.: Legal implications of exercise testing. Cardiovascular Medicine 3:1137, 1978.
- Karsh, D.S., Michaelson, S.P., Langou, R.A., Cohen, L.S., Wolfson, S.: Retrograde left ventricular catheterization in
patients with an aortic valve prosthesis. Amer. J. Cardiol. 41:893, 1978.
- Steere, A.C., Batsford, W.P., Weinberg, M., Alexander J., Berger, H.J., Wolfson, S., Malawista, S.E.: Lyme
carditis: Cardiac abnormalities of Lyme Disease. Ann. of Int. Med. 93:8, 1980.
- Mason, S.J., Wolfson, S.: Angina Pectoris: Guide of medical management. 16:66, 1980.
- Scheinman, S.J., Poll, D.S., Wolfson, S.: Acute cardiac failure and hepatic ischemia induced by Disopyramide
phosphate. Yale J. of Biol. and Med. 53:361, 1980.
- Tacket, C.O., Good, N., Berger, H.J., Wolfson, S.: Rose of prostaglandins E2 and F2 during myocardial ischemia. In
"Prostaglandins in Cardiovascular and Renal Function," 1980.
- Lundell, D.C., Hammond, G.L., Geha, A.S., Laks, H., Wolfson, S.: Randomized comparison of the modified wire-guided and
standard intra-aortic balloon catheters. J. of Thoracic and Cardiovasc. Surg. 81:297, 1981.
- Scheinman, S.J., Poll, D.S., Wolfson, S.: Acute cardiac failure and hepatic ischemia induced by Disopyramide
phosphate. Yale J. of Biol. and Med. 53:361, 1980.
- Marx, P., Jaffe, C., Laks, H., Wolfson, S.: Delayed post-cardiac surgery tamponade producing localized right atrial
compression. Catheterization and cardiovascular diagnosis. 7:275, 1981.
Abstracts:
- Wolfson, S. and Krasnow, N.: ECG effects of beta-sympathetic blockade. Clin. Res. 12:455, 1964.
- Wolfson, S., Heinle, R.A., Kemp, H.C. and Gorlin, R.: Actions of propranolol in angina pectoris. Clin. Res. 14:254, 1966.
- Wolfson, S., Sullivan, J.M., and Gorlin, R.: Actions of propranolol in angina pectoris. Circ. 34: Suppl. III-241, 1966.
- Herman M.V., Sullivan, J.M., Heinle, R.A., Kemp, H.C., Wolfson, S., Gorlin, R.: Asynergy of ventricular contraction: An
important cause of cardiac failure in coronary heart disease. J. Clin. Invest. 45:1022, 1966.
- Wolfson, S., Parker, G., Tsao-Wu, N. and Gorlin, R.: Implications of abnormal segmental shortening in the human left
ventricle. Clin. Res. 15:277, 1967.
- Matloff, J.M., Wolfson, S., Harken, D.E., and Gorlin, R.: Control of post-cardiac surgical tachycardias with
propranolol. Circ. 35: Suppl II-184, 1967.
- Wolfson, S., Amsterdam, E.A. and Gorlin, R.: Prognostic significance of angina therapy. Preliminary report. Circ.
36: Suppl II-274, 1967.
- Amsterdam, E.A., Wolfson, S., and Gorlin, R.: Effect of therapy on survival in angina pectoris. Ann. Int. Med. 68:1151,
1968.
- Amsterdam, E.A., Wolfson, S., and Gorlin, R.: Evaluation of long-term use of propranolol in angina pectoris. Amer. J. of
Cardiol. 23:104, 1969.
- Amsterdam, E.A., Most, A.S., Wolfson, S., Kemp, H.C., Gorlin, R.: Relation of angiographically documented coronary artery
disease to mortality. Ann. Int. Med. 72:780, 1970.
- Wolfson, S., Phillips, S.L., and Schechter, E.: Effects of specific myocardial beta blockade in angina pectoris. Amer.
J. Cardiol. 26:666, 1970.
- Wolfson, S., Acosta, A.E., Rose, L.I., Parisi, A.F., Engelman, K.: Effects of conditioning on plasma catecholamine levels
during exercise in patients with coronary artery disease. Clin. Research 19:714, 1971.
- Wolfson, S., Acosta, A.E., Rose, L.I., Parisi, A.F., Engleman, K.: Effects of conditioning on plasma catecholamine levels
during exercise in patients with coronary artery disease. Amer. J. Cardiol. 29:297, 1972.
- Kisslo, J.A., Wolfson, S., Hammond, G.L., Cohen, L.S.: Echocardiography in the assessment of left ventricular function after
saphenous vein bypass. Circ. 46, Suppl II-68, 1972.
- Ross, A.M., Wong, B.Y.S., Rosenthal, J.E., Wolfson, S., Cohen, L.S.: Hemodynamic changes associated with abnormal lactate
metabolism during atrial pacing. Circ. 46, Suppl II:74: 1972.
- Bryson, A.L., Parisi, A.F., Schechter, E., Wolfson, S.: Exercise-induced left-threatening ventricular arrhythmias - cessation
following coronary bypass surgery. Circ. 48: Suppl IV-40, 1973.
- Wolfson, S., Grand, D., Ross, A.M., Cohen, L.S.: Risk of death related to coronary rteriography: Role of left coronary
lesions. Circ. 48: Suppl. IV-88, 1973.
- Langou, R.A., Cohen, L.S., Wolfson, S., Sheps, D.S., Wong, B.Y.S., Horner, D.W., Glenn, W.W.L., Ondine's Curse: response
to electrophrenic nerve respiratory. Circ. 48: Suppl. IV-114, 1973.
- Cohen, L.S., Langou, R.A., Wolfson, S., Porterfield, D., Mitchell, J.H.: Hemodynamic studies of sequenced and nonsequenced
external counterpulsation. Amer. J. Cardiol. 33:131, 1974.
- Schrumpf, J.C., Sheps, D.S., Wolfson, S., Aronson, A.L., Cohen, L.S.: Effects of propranolol on hemoglobin oxygen affinity in
the anginal syndrome. Amer. J. Cardiol. 33:170, 1974.
- Ross, A.M., Hammond, G.L., Cohen, L.S., Wolfson, S.: Nonvisualized coronary arteries on restudy following saphenous vein
bypass grafts. Clin. Res. 22:302A, 1974.
- Zaret, B.L., Vlay, S., Freedman, G.S., Wolfson, S., Cohen, L.S.: Quantitative correlates of resting potassium-43 perfusion
following myocardial infarction in man. Circ 49 and 50. Suppl. III-4, 1974.
- Wolfson, S., Olson, E.G., Langou, R.A., Goodyer, A.V.N., Cohen, L.S.: N-dimethylisopropyl propranolol (SC-27761), an analogue
without beta blocking on local anesthetic actions. Circ. 49 and 50: Suppl. III-37, 1974.
- Berger, H.J., Zaret, B.L., Speroff, L., Cohen, L.S., Wolfson, S.: Myocardial prostaglandin release during acute ischemia
induced by atrial pacing in man and coronary occlusion in dogs. Circ. 49 and 50: Suppl. III-122, 1974.
- Langou, R.A., Wolfson, S., Olson, E.G., Cohen, L.S.: Decreased myocardial oxygen consumption after orthostatic
tilting. Circ. 49 and 50: Suppl. IV-184, 1974.
- Berger, H.J., Zaret, B.L., Speroff, L., Cohen, L.S., Wolfson, S.: Regional localization of prostaglandin release from
myocardium during acute ischemia induced by coronary occlusion in dogs. Clin. Res. 23:172A, 1975.
- Costin, J.C., Cohen, L.S., Wolfson, S.: Hemodynamic and metabolic actions of B-adrenergic blockade in skeletal
muscle. Clin. Res. 23:172A, 1975.
- Zaret, B.L., Donabedian, R.K., Wolfson, S., Puri, S., Freedman, G.S., Cohen, L.S.: Dual radionuclide study of myocardial
infarction: Relationships between potassium-43, technetium-99M pyrophosphate and myocardial creatine phosphokinase. Clin. Res. 23:172A, 1975.
- Farry, J.P., Simon, A.L., Ross, A.M., Cohen, L.S., Wolfson, S.: Quantitative angiographic assessment of the mitral annulus in
the prolapsing leaflet syndrome. Circ. 52:II-12, 1975.
- Wolfson, S., Costin, J.C., Cohen, L.S.: Evaluation of left ventricular mechanoreceptors during cardiac angiography and atrial
pacing. Amer. J. Card. 37:183, 1976.
- Kirmser, R., Berger, H.J., Cohen, L.S., Wolfson, S.: Effect of indomethacin, a prostaglandin inhibitor, on epicardial ST
elevation and myocardial flow after coronary occlusion. Circ. 54:II-194, 1976.
- Wolfson, S., Geha, A.S., Hammond, G.L., Langou, R.A., Cohen, L.S.: Preliminary report: Modification of intra-aortic
balloon for pressure measurement, contrast injection and guide wire passage. Amer. J. Card. 39:260, 1977.
33.Kirmser, R., Berger, H.J., Cohen, L.S., Wolfson, S.: Beneficial effects of
prostaglandin E2 on blood flow distribution during myocardial ischemia in dogs. Amer. J. Card. 39:280, 1977.
- Wolfson, S., Johnson, H.L., Johnson, A.C., Addabbo, M., Cohen, L.S.: Differential effects of indomethacin and
acetyl-salicylic acid on coronary flow and epicardial ST segment elevation after coronary occlusion. Clin. Res. 25:279A, 1977.
- Wolfson, S., Tacket, C., Good, N., Kirmser, R.J., Addabbo, M., Cohen, L.S.: Role of prostaglandin E during coronary
occlusion. Circ. 55 and 56, Suppl. III-122, 1977.
- Alexander, J., Wolfson, S., Kelley, M.J., Cohen, L.S., Langou, R.A.: Angiographic appearance of coronary arteries in
constrictive pericarditis. Am. J. Card. 41:445, 1978.
Chapters:
- Wolfson, S., and Gorlin, R.: Effects of propranolol in the diseased heart. In "Cardiovascular Beta Adrenergic
Responses." Ed. Kattus, A.A., Jr., Ross, G., 1970, p. 151.
- Wolfson, S., Amsterdam, E.A., Gorlin, R.: Rational for the use of beta blockade as therapy for angina pectoris. In
"Coronary Heart Disease," Russek, H.I. and Zohman, B.L. ed. Lippincott, J.P., Comp., 1971, p. 307.
- Wolfson, S., Cohen, L.S.: Beta adrenergic blocking drugs: A clinical appraisal. In "Drugs in Cardiology, Part
I." Ed. E. Donoso, 1975.
- Wolfson, S., Costin, J.C.: Medical therapy of angina pectoris. In "Angina Pectoris," Ed. E. Donoso, 1977.
Reviews :
- Cardiac Catheterization and Angiography, Second edition, Edited by William Grossman. 427 pp., illustrated. Philadelphia,
Lea and Febiger, 1980. Reviewed in The New England Journal of Medicine, May 7, 1981.
- Coronary Angiography: In the Medical and Surgical Treatment of Ischemic Heart disease, by Guillermo Pujades. 553 pp.,
illustrated. New York, McGraw-Hill, 1980. Reviewed in the New England Journal of Medicine, May 7, 1981.
- Diagnostic Methods in Clinical Cardiology, Edited by Peter F. Cohn and Joshua Wynne. 377 pp., illustrated. Boston, Little,
Brown, 1982. Reviewed in The New England Journal of Medicine, August 26, 1982.
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